Friday, 03 April 2020 | 14:00 WIB

This Drug May be Able to Regenerate Rotten Teeth

This Drug May be Able to Regenerate Rotten Teeth (flickr)

LONDON, NETRALNEWS.COM - A recent study suggests that rotten teeth regeneration is possible. A treatment to regenerate rotten teeth could reduce the need for fillings in the future.

The therapy enhances the natural ability of teeth to repair themselves through the activation of stem cells in the soft pulp at the centre. Prof Paul Sharpe, who led the work at King’s College London, said a trial, in mice, showed that when defects were filled with a biodegradable sponge soaked in the drug, the tooth was gradually able to rebuild itself.

Restoring the tooth’s original dentine structure is preferable because dental cements used in conventional fillings weaken the tooth, leave it prone to future infections and inevitably erode or detach.

In the case of large cavities, the tooth may eventually need to be extracted after undergoing multiple treatments. The new method, which would encourage natural tooth repair, has the potential to eliminate these issues, according to the scientists.

The new treatment would not eliminate the need for the dentist’s drill, however, since decaying sections of the tooth would still need to be removed. The therapy relies on a drug called tideglusib, which has been assessed as a potential Alzheimer’s treatment, and which is known to be safe for clinical use.

The study is published in Scientific Reports.